Research & Trials
Emerging Research
Clinical research is expanding the list of diseases and conditions that may be treatable with cord blood and cord tissue.
Cord Blood Stem Cell Research
Right now, researchers are looking for new potential ways to heal the body using cord blood stem cells. Clinical trials are underway around the world to determine how stem cells from cord blood could be used in the future to treat:
Diagnosis | Trial Site | Trial ID |
---|---|---|
Autism | US (Duke) US (Sutter Health) |
NCT02176317 NCT01638819 |
Acquired Hearing Loss | US (Florida) | NCT02038972 |
Cerebral Palsy | US (Duke) US (Texas Health Science Center) US (Georgia Regents University) |
NCT01147653 NCT01988584 NCT01072370 |
Hypoplastic left heart syndrome | US (Duke) US (Mayo Clinic) |
NCT01445041 NCT01883076 |
Metabolic disorders | US (Duke) | NCT02254863 |
Stroke – Pediatric | US (Florida) | NCT02460484 |
Stroke – Adult | US (Duke) | NCT02397018 |
Emerging Cord Blood Technologies:
Advancements in technology may enable the number of cells available from cord blood collections to be expanded.
The important benefits of cell expansion would be:
- Extending the period over which cord blood stem cells may be used, as treatments for adults require more stem cells than treatments for a child.
- Increasing the potential number of therapies from one unit of cord blood.
Cord Tissue and Mesenchymal Stem Cell Research
Expectant parents can now bank a segment of their baby’s umbilical cord tissue, which is a rich source of mesenchyal stem cells (MSCs) that may have future potential to help repair and heal the body.
Researchers are now testing the potential of MSCs, derived from umbilical cord tissue, bone marrow or adipose tissue in a variety of clinical trials for the following conditions and diseases:
Diagnosis | Trial Site | Trial ID |
---|---|---|
Acute respiratory distress syndrome | US | NCT02097641 |
Alzheimer’s disease | China | NCT01547689 |
Cardiovascular disease | US | NCT02032004 |
Cardiac repair | US | NCT01557543 |
Crohn’s disease | US | NCT02150551 |
Diabetes (Type 1) | Sweden | NCT02057211 |
Liver disease | China | NCT01844063 |
Multiple sclerosis | Canada | NCT02239393 |
Osteoarthritis | Canada | NCT02351011 |
Rheumatoid arthritis | Panama | NCT01985464 |
Stroke | US | NCT01849887 |
Although scientists are optimistic that new cutting-edge therapies will result from cord tissue research, the application of cord tissue MSCs is in the early stage of clinical development.